The winger suffered an acute appendicitis which has ruled him out of the Wembley game having already gone under the knife.
The hope was the Three Lions star, who scored for his country at Qatar 2022, would feature on Sunday having trained in the build-up but felt unwell and has had to miss the qualifier.
But the Man City ace won’t be available for the fixture, handing Gareth Southgate another blow with Luke Shaw also unavailable following his red card in the 2-1 win over Italy.
How long does it take to recover from appendicitis?
The NHS advises not to return to ‘strenuous activities’ until four to six weeks following surgery.
What games could Phil Foden miss?
It is now likely that Foden will miss the entirety of April and the beginning of May following surgery.
Man City open May with gammes at home to West Ham at Leeds, at which point Foden should be back in training.
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